Heart Imaging Genetics Knowledge Portal (Heart-KP)

Integrating knowledge and data for human heart research

1. Imaging Genetics Online Server

We build a GWAS browser using the PheWeb tool to explore GWAS results for heart imaging traits. Currently, we support GWAS results of 82 traits trained in the UKB British cohort (n~31,000), including 64 left ventricle traits, 4 left atrium traits, 4 right ventricle traits, 4 right atrium traits, 3 ascending aorta traits, and 3 descending aorta traits.

2. GWAS Summary Statistics Data Download

GWAS summary statistics for the 82 heart imaging traits can be free download from Zenodo: https://zenodo.org/record/7239166 Reference Bingxin Zhao et al. , Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images (2023). Science. LINK
Also, welcome to check out our Brain Imaging Genetics Knowledge Portal (BIG-KP) !!
Change log Sep 17, 2021- Initial launch of websiteOct 27, 2021- GWAS summary statistics of 82 CMR traits shared on ZenodoNov 04, 2022 - Update of GWAS summary statistics of 82 CMR traits on Zenodo and online server

Heart-KP website maintenance

Zirui Fan ziruifan@upenn.edu Yue Yang yyang96@unc.edu Bingxin Zhao bxzhao@upenn.edu

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